A
male
age
36-40,
anonymous
writes:My future mother-in-law commented on how there is a lot of diabetic-related history on her side of the family.My fiancée eats a lot of junk food, but is really thin and exercises a lot... is there a disposition for her (or our future children) to develop diabetes? Reply to this Question
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Fancy yourself as an agony aunt? Add your answer to this question! A
female
reader, littleBB  +, writes (6 May 2011):
Type I or type II diabetes? I am assuming type II where there is a family predisposition to the desease but no single gene hereditary pattern. SIngle gene hereditary patterns are more likely to determine deseases whereas familiary predisposition is linked to many genetic traits which interact with the environment. Meaning that there must be the right combination of many genes (not identified yet!!!) and those must find the right enviromental conditions in order for the desease to develop.
It is not sure she got the genes which predispose her to the desease, and such desease usually develops in overweight people. Having the family trait makes her more desease prone in case she gets overweight (hence the environment contributtion). If you are talking about type I diabetes the story is totally different there are well identified genes (called DR) connected with the desease, this desease appears in young people and is the result of an infection that leads to the destruction of the cells which produce insulin. I think you a re talking about type II diabetese, which is preventable with waight control and calory intake, nothing to worry about idf she is fit.
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